Specifically, we investigate its capacities for plastic reorganization (i.e., synaptic re-wiring and learning). Using optical imaging techniques combined with modelling, we aim at deciphering the brain‘s computational strategies that lead to perception and behavior. Optical imaging is unique in its capability of capturing the activity of millions of neurons at once using light. In combination with optogenetics (i.e., light stimulation and recordings of specific target neurons and neuronal subnetworks) our approach provides access to both theoretical and experimental questions dealing with the highly dynamic activity patterns observed across the brain.
Jancke D (2017).
Catching the voltage gradient — Asymmetric boost of cortical spread generates motion signals across visual cortex: a brief review with special thanks to Amiram Grinvald.
Neurophoton. 4(3): 031206. doi: 10.1117/1.NPh.4.3.031206.
Spoida K, Eickelbeck D, Karapinar R, Eckhardt T, Mark MD, Jancke D, Ehinger BV, König P, Dalkara D, Herlitze S, Masseck OA (2016).
Melanopsin variants as intrinsic optogenetic On and Off switches for transient versus sustained activation of G protein pathways.
Curr Biol. 26: 1206-1212.
Rekauzke S, Nortmann N, Staadt R, Hock HS, Schöner G, Jancke D (2016).
Temporal asymmetry in dark-bright processing initiates propagating activity across primary visual cortex.
J Neuroscience 36: 1902-1913. doi: 10.1523/NEUROSCI.3235-15.2016 (Open Access)
Institut für Neuroinformatik
Ruhr University Bochum
44780 Bochum
Germany
Phone Office: +49(0)234-32-28967
Phone: +49(0)234-32-27845
E-Mail: dirk.jancke@rub.de
Vice Speaker - CRC 874, Board - Research Dept. of Neuroscience, PhD Committee & Study Commission - IGSN, Directorate - INI
The Institut für Neuroinformatik (INI) is a central research unit of the Ruhr-Universität Bochum. We aim to understand the fundamental principles through which organisms generate behavior and cognition while linked to their environments.
