Let thoughts shine

Voltage-sensitive dyes let thoughts light researcher examines movement in brain.

How does the brain perceive movements? This question is being studied by PD Dr. Dirk Jancke at the Ruhr-Universität Bochum with a special optical process.

In a special section of the journal "Neurophotonics", Jancke describes the insights he was able to achieve thanks to the use of voltage-sensitive dyes, while honoring Prof. Amiram Grinvald - one of the most important researchers in this field.

When the voltage increases
The neuro-computer scientist Dirk Jancke regularly sheds light on his research, and not just in the figurative sense: In his laboratory, he transforms the activity of brain cells into light. To do this, the scientist uses fluorescent dyes with a special property: they react to changes in the electrical voltage in their environment by making them glow stronger or weaker. So if a cell is activated in the brain, the electrical voltage rises above the cell membrane and the dye fluoresces more. The imaging technique using the voltage-sensitive dyes is called "Voltage-Sensitive Dye Imaging" or VSDI for short. His discovery paved the way for many new insights in neuroscience. "Stress-sensitive dyes give us the best spatiotemporal resolution for our observations at the moment, so you can view a larger part of the brain in milliseconds at the same time," says Jancke.

Link to original press release:
http://www.ruhr-uni-bochum.de/sfb874/presse/pressemeldungen/Gedanken_leuchten_de.html (deutsch)
https://www.ruhr-uni-bochum.de/sfb874/presse/pressemeldungen/Gedanken_leuchten.html (english)

PD Dr. Dirk Jancke

Institut für Neuroinformatik NB2/27
Ruhr University Bochum
44780 Bochum

Phone Lab:+49 (0)234 32 28967
Phone Office: +49 (0)234-32-27845
E-Mail: dirk.jancke@rub.de